Anti-inflammatory therapies for stroke prevention: a review from our lab

Our new review on translating anti-inflammatory therapies for atherosclerotic stroke prevention in Neurology👇

As opposed to manifestations of atherosclerosis in other vascular beds, stroke prevention is more nuanced due to heterogeneity of underlying etiology.

Our review
👉outlines preclinical, genetic, and epidemiologic evidence linking inflammation to atherosclerotic stroke
👉analyzes coronary artery disease trials and the first stroke-specific colchicine trial 👉discusses the balance between personalization of prevention strategies and pragmatism in trial design
👉summarizes under development anti-inflammatory interventions beyond colchicine that target next-generation targets (IL6, CCL2/CCR2 etc.)

Link to the article: https://www.neurology.org/doi/10.1212/WNL.0000000000214214